Acinic cell carcinoma of the oral and maxillofacial region: an international multicenter study

Abstract The aim of this study was to describe the prevalence, clinicopathological, and prognostic features of acinic cell carcinoma (AciCC) of the oral and maxillofacial region. AciCC cases were retrospectively retrieved from 11 pathology centers of three different countries. Medical records were examined to extract demographic, clinical, pathologic, and follow-up information. A total of 75 cases were included. Females (65.33%) with a mean age of 45.51 years were mostly affected. The lesions usually presented as an asymptomatic (64.28%) nodule (95.66%) in the parotid gland (70.68%). The association of two histopathological patterns was the most common finding (48.93%) and the tumors presented mainly conventional histopathological grades (86.11%). Surgical treatment was performed in the majority of the cases (59.19%). Local recurrence was observed in 20% of the informed cases, regional metastasis in 30.43%, and distant metastasis in 12.50%. The statistical analysis showed that the cases with a solid histopathological pattern (p=0.01), high-grade transformation (p=0.008), recurrence (p=0.007), and regional metastasis (p=0.03) were associated with poor survival. In conclusion, high histopathological transformation, presence of nodal metastasis, and recurrence were prognostic factors for AciCC of the oral and maxillofacial region.

Virtual learning object about oral ulcerative lesions: controlled educational intervention study

Abstract The aim of this study was to develop a virtual learning object (VLO) to teach undergraduate dental students about the diagnostic and therapeutic approaches to oral ulcerative lesions. The VLO was developed with information on the diagnostic process, lesion classification, and clinical-surgical management of oral ulcerative lesions. The VLO content was initially validated by a group of specialists. Learning was evaluated in a sample of 58 undergraduate dental students, divided into control group (conventional theoretical class, n = 29) and intervention group (interaction with VLO, n = 29). All students answered a pre-test and post-test questionnaire. The VLO group also answered a specific questionnaire on the evaluation of the VLO. Both quantitative and qualitative descriptive analyses were performed. The validation showed that professors and students considered the VLO adequate. The use of the VLO was recommended by 100% of professors and 86.6% of students. In the intervention group, the results showed a significantly higher number of correct answers in the post-test (p < 0.01). In conclusion, the VLO proved to be a useful tool for teaching oral medicine, contributing significantly to the knowledge of ulcerated lesions in the mouth.

Investigation of oral and general health status and IL-1β gene polymorphism as risk factors for oral mucositis in hematopoietic stem cell transplantation patients

Abstract: The aim of the present study was to analyze the relationship of OM with possible risk factors such as oral health condition, immunological status and IL-1β profile in patients submitted to hematopoietic stem cell transplantation (HSCT). Fifty-four individuals submitted to HSCT were included. All patients received previous dental treatment and photobiomodulation (PBM) as the institutional OM preventive protocol. OM scores, immune status, and IL-1β levels were determined during the conditioning period and at D+3 and D+8 after HSC infusion. IL-1β gene polymorphism was also analyzed during conditioning. Possible associations of OM with risk factors were analyzed using conditional Fisher's exact test. OM was observed in 34 patients (62.9%) classified as Grade 1 (13 patients/24.1%), Grade 2 (14 patients/25.9%), Grade 3 (3 patients/5.5%), and Grade 4 (4 patients/7.4%). Allogeneic HSCT individuals exhibited a higher OM grade than autologous subjects. Moreover, an association was observed between severe OM and severe gingivitis (p = 0.01), neutropenia (p = 0.03), and leukopenia (p = 0.04). A significant association between OM and lower IL-1β levels was detected at three time points, i.e., conditioning (p = 0.048), D+3 (p = 0.01), and D+8 (p = 0.005). The results showed that IL-1β gene polymorphism was not associated with OM. Our study provided important insights into the scope of OM risk factors in the setting of HSCT. Patients submitted to HSCT with severe gingivitis prior to chemotherapy and with severe neutropenia and leukopenia exhibited a higher OM grade. Further investigation will be necessary to better understand the exact role of IL-1β in the context of OM pathobiology and to validate cytokine analysis in larger cohorts.

Distance learning course improves primary care dentists' diagnosis and self-efficacy in the management of oral lesions

Abstract Oral cancer represents a public health issue because of its high mortality rate, resulting mainly from diagnostic delays. Insufficient training in oral diagnosis is usually perceived by dentists. Distance learning could be used as an auxiliary tool to bridge that gap. This study evaluated the impact of a distance learning course on oral mucosal lesion diagnosis offered to public healthcare dentists. Participants of an online course answered a pretest/posttest comprising clinical images of 30 clinical cases. Participants were questioned about the diagnosis and informed their decision on the cases (referring the cases to a specialist or managing them themselves), as a parameter of perceived self-efficacy. A total of 442 dentists enrolled in the course. Their pass rate was 97%. Classification of the nature of the lesions, diagnostic hypotheses, sensitivity, and specificity improved by 13.4%, 10.0%, 13.4%, and 6.6%, respectively (p<0.01, Wilcoxon test). Regarding management, there was a 16.6% reduction in the intention to refer cases, while confidence in the diagnosis of benign lesions increased by 40%. A distance learning course may be useful in continuing education actions for primary care dentists, improving their diagnostic abilities and encouraging them in the management of oral lesions. Moreover, this strategy could contribute to disseminating knowledge to remote regions, particularly among primary health care professionals.

Prognostic factors from squamous cell carcinoma of the hard palate, gingiva and upper alveolar ridge

Abstract: The purpose of this study was to evaluate the clinicodemographic characteristics and treatment protocol as prognostic factors in patients with oral squamous cell carcinoma (OSCC) of the hard palate, upper gingiva, and alveolar ridge (HPUGAR). This retrospective cohort study collected data of patients treated in two head and neck surgery departments in southern Brazil between 1999 and 2021. Information on clinicodemographic data, habits, site, size, clinical aspect, clinical staging, cervical metastasis, treatment, and survival was collected. Associations between independent variables and outcomes were assessed using Pearson's chi-square test and binary regression. Kaplan-Meier test was employed to compare the survival between the neck approaches. Forty-one patients were included; most were male (61%), with a mean age of 68.8 (± 13.9) years. The consumption of tobacco (p = 0.003) and alcohol (p = 0.02) was significantly higher in male than in female patients. The main clinical features observed in the study sample were lesions larger than 2 cm (48.7%), no cervical (90.2%), or distant metastasis (90.2%). Surgery alone was the main treatment approach (48.8%). The watch-and-wait strategy was adopted in 34 cases (83.0%), while elective neck dissection was applied in five (12.2%). Only two patients with cN0 disease (4.9%) presented with cervical metastasis at follow-up. Eight patients (12.2%) died of the disease. Clinicodemographic variables, habits, surgical margins, and histological subtype were not significantly associated with cervical metastasis or survival. Cervical metastasis (p = 0.004) was associated with poor survival. No difference was detected in survival between different neck approaches (p = 0.28). Cervical metastasis and local recurrence are negative prognostic factors for HPUGAR OSCC.

Cistos e tumores odontogênicos: estudo retrospectivo dos casos diagnosticados no período de 10 anos em um hospital no sul do Brasil / Odontogenic cysts and tumors: a retrospective study of the cases diagnosed in a period of 10 years in a southern Brazilian hospital

Introdução: as lesões odontogênicas (LOs) compreendem um grupo heterogêneo de patologias orais e maxilofaciais que apresentam características distintas. O objetivo do presente estudo foi identificar as características clínico--patológicas das LOs diagnosticadas em um hospital da região sul do Brasil. Materiais e métodos: foi realizado um estudo retrospectivo para levantamento dos casos com diagnóstico histopatológico de LOs no período entre 2007 e 2017. Os laudos dos pacientes foram avaliados para extração das características clínico-patológicas e dos diagnósticos histopatológicos de cada caso. Resultados: um total de 255 casos de LOs foram identificados. Destes casos, 197 (77%) cistos odontogênicos e 58 (23%) tumores odontogênicos foram coletados, sendo que somente um caso (0,39%) possuiu o diagnóstico de neoplasia odonto-gênica maligna. Os diagnósticos mais prevalentes foram cisto radicular (32,5%) e cisto dentígero (31,76%), seguidos de ceratocisto odontogênico (10,98%), odontoma (10%) e ameloblastoma (10%). A maioria dos casos acometeu mandíbula (53,7%), com uma discreta predileção pelo sexo feminino (51%). A média de idade foi de 34±20,53 anos. Discussão: os dados apresentados corroboram com a literatura no que se refere à raridade do diagnóstico de tumores odontogênicos. Conclusão: o presente estudo demonstrou as principais características clínico-pato-lógicas de LOs diagnosticadas em um hospital no sul do Brasil, contribuindo para um maior conhecimento do perfil destas lesões.

Introduction: odontogenic lesions (OLs) represent a heterogeneous group of oral and maxillofacial patho-logies presenting distinct characteristics. The present study aimed to identify the clinical and pathological characteristics of OLs diagnosed in a southern Brazilian hospital. Materials and methods: a retrospective study was performed to evaluate cases with histopathological diagnosis of OLs identified in the period between 2007 and 2017. The patient's medical records were evaluated in order to obtain the clinical and pathological charac-teristics and the histopathological diagnosis from each case. Results: a total of 255 cases of OLs were identified. From these, 197 (77%) odontogenic cysts and 58 (23%) odontogenic tumors were surveyed, with only one case (0,39%) of a malignant odontogenic neoplasm. The most prevalent diagnosis were radicular cyst (32.5%) and den-tigerous cyst (31.76%), followed by odontogenic keratocyst (10.98%), odontoma (10%) and ameloblastoma (10%). The majority of the cases affected the mandible (53.7%) with a slight preference by female individuals (51%). The mean age was 34±20.53 years old. Discussion: the presented data are in accordance with the literature regarding the rarity of the diagnosis of odontogenic tumors.Conclusion: the present study demonstrated the main clinical and pathological characteristics of OLs diagnosed in a southern Brazilian hospital, contrib-uting to a better understanding of these injuries profiles.

Analysis of referrals to the stomatology service in a Southern Brazilian hospital: a retrospective study

Abstract This paper intends to describe the demand for referrals to the stomatology service requested by the medical teams for inpatients in a reference hospital in the south of Brazil. This research is a retrospective cross-sectional descriptive study focusing on data collection and assessment of information about referrals to the stomatology unit carried out from January 2008 to December 2018. All information was obtained from the hospital management software database, then transferred and analyzed individually for descriptive statistics. A total of 4433 cases were referred to the stomatology team, with an average of 403 cases by year. Hematology/hemato-oncology (37.3%) was the specialty asking for the majority of the referrals, followed by Oncology (20.4%) and Pneumology (8.2%). The mean patients' profile was males (55.5%), receiving a diagnosis of oral mucositis (43.5%), and with the first and second decades of life being the most prevalent ones (34.9%), with a mean age of 34.8±22.3 years. The most common treatment performed by the stomatology team was the photobiomodulation therapy (44.8%). This retrospective study demonstrated the important profile of the stomatological care in hospitalized patients from a specific hospital, especially referred by the hematology/hemato-oncology team. These results evidenced the importance of the stomatology specialty in the hospital environment.

Mortality due to oral and oropharyngeal cancer in Uruguay from 1997 to 2014

Abstract Oral and oropharyngeal cancer is considered a public health problem in several countries due to its high incidence and mortality rate. Objective: This study aimed to analyze oral and oropharyngeal cancer mortality in Uruguay from 1997 to 2014 by age, sex and country region. Methodology: A time series ecological study using secondary data was performed. Data on mortality due to oral and oropharyngeal cancers were obtained from the Vital Statistics Department of Uruguay's Ministry of Public Health. Results: The cumulative mortality rate due to oral and oropharyngeal cancer over the study period was of 19.26/100,000 persons in women and 83.61/100.000 in men, with a mean annual rate of 1.75/100,000 in women and 7.60/100,000 in men. Mortality rate from both sites during the study period was 4.34 times higher in men than in women. Malignant neoplasms of other parts of the tongue and base of tongue showed the highest mortality rate. The means of the annual coefficients of deaths were higher for the age groups between 50 and 69 years. Higher mortality rates of oral and oropharyngeal cancer were observed in Artigas (4.63) and Cerro Largo (3.75). Conclusions: Our study described a high mortality rate for oral and oropharyngeal cancer in Uruguay from 1997 to 2014. According to the country's health department, men, tongue cancer, and oral cavity had higher mortality rates, with some variation. Prevention strategies with control of risk factors and early diagnosis are necessary to improve survival in the Uruguayan population.

TGF-ß1 and its association with clinicopathological features, proliferative activity and prognosis in oral squamous cell carcinoma: an immunohistochemical study

Introduction: The prognostic value of transforming growth factor beta-1 (TGF-ß1) in oral cancer remains unclear. Therefore, the aim of this study was to evaluate TGF-ß1 expression in oral squamous cell carcinoma (OSCC) samples and its association with clinicopathological data, tumor proliferative activity, and patients' prognosis. Methods: A total of 68 patients with histopathological diagnosis of OSCC were included, as well as 9 cases of normal oral mucosa for comparison purposes. The OSCC sample was categorized according to patients' outcomes in favorable prognosis (n=30) or unfavorable prognosis (n=38). Immunohistochemical staining for TGF-ß1 and Ki-67 were performed. The slides were semi-quantitatively and quantitatively evaluated for TGF-ß1 and Ki-67, respectively. Results: TGF-ß1 was significantly increased in OSCC compared to normal oral mucosa (<0.01). An inverse correlation was found between TGF-ß1 and Ki67 staining in OSCC (p=0.01). No association was found between TGF-ß1 expression and OSCC clinicopathological features, prognosis or survival. Conclusions: TGF-ß1 had no prognostic value and appears to maintain its suppressive role concerning cell proliferation. (AU)

Impact of highly active antiretroviral therapy in the development and remission of oral plasmablastic lymphoma.

Plasmablastic lymphoma (PBL) represents a rare type of non-Hodgkin lymphoma associated with human immunodeficiency virus (HIV) infection. The impact of highly active antiretroviral therapy (HAART) in this tumor is poorly known due to its small incidence. This study reports a case of a 33-year-old HIV-positive woman who was referred to the Stomatology Department complaining about a painful gingival growth and cervical nodule both with 20 days of evolution. The lesions appeared 7 months after the patient stopped HAART. The final diagnosis was PBL. After resuming HAART for 45 days, the gingival lesion presented complete remission. The patient continued with HAART alongside chemotherapy. At 24 months follow-up, the patient was stable. The dental surgeon plays an essential role in orientation and retention in care of HIV patients once the adherence of HAART seems to play an important role in PBL development and response to treatment.

Oral mucosal lesions and their association with sociodemographic, behavioral, and health status factors

The aim of this study was to evaluate the frequency of oral mucosal lesions and their associations with sociodemographic, health, and behavioral factors in a southern Brazilian population. Information was collected from participants (n = 801) using a structured questionnaire during an oral cancer screening campaign held at an agribusiness show in southern Brazil in 2009. Data were described using frequency distributions or means and standard deviations. Associations between independent variables and outcomes were assessed using the Chi-squared test. A total of 465 lesions were detected (actinic cheilitis: n = 204, 25.5%; candidiasis: n = 50, 6.2%; fibrous inflammatory hyperplasia: n = 42, 5.2%; ulceration, n = 33, 4.1%; hemangioma: n = 14, 1.7%; leukoplakia: n = 11, 1.4%). Candidiasis, actinic cheilitis, and fibrous inflammatory hyperplasia were associated significantly with literacy. Actinic cheilitis was also associated significantly with sun exposure and hat use, and leukoplakia was associated with smoking. The high frequency of oral mucosal lesions observed highlights the importance of education about risk factors. Additionally, training of health professionals, mainly those from public health services, in the use of preventive and community education strategies is needed.

Tumor de células granulares: relato de dois casos / Granular cell tumor: report of two cases

O tumor de células granulares (TCG) é uma neoplasia benigna incomum de tecidos moles. Dorso e borda lateral de língua são os sítios mais comumente afetados. Clinicamente, apresenta-se como uma lesão nodular, firme à palpação, bem delimitada, de crescimento lento. O objetivo deste trabalho é relatar dois casos clínicos de TCG mostrando seu aspecto clínico, histopatológico e discutir as hipóteses de diagnóstico e conduta realizada em cada caso.

The granular cell tumor (GCT) is an uncommon benign neoplasm of soft tissue. The sites most commonly affected are the dorsum and lateral border of the tongue. Clinically it presents as a nodular lesion, firm to palpation, well-defined with slow-growing. The aim of this study is to report two cases of GCT showing its clinical and histopathological aspects, and discuss the diagnosis and management of each case.

Expansive lesion of the anterior mandible in child a case report of calcifying cystic odontogenic tumor

The calcifying cystic odontogenic tumor is an uncommon lesion that occurs in both jaws. This odontogenic neoplasm is generally asymptomatic, found either in routine radiographic examination or when causing bone expansion. The purpose of this report was to describe a case of calcifying cystic odontogenic tumor involving mandible in a 9-year-old girl, as well as discuss the importance of careful diagnostic procedures for the correct final diagnosis and establishment of the most appropriate treatment of this uncommon odontogenic lesion that can affect the patients of the pediatric group.

Síndrome de Cushing como complicação do tratamento de líquen plano oral erosivo / Cushing´s Syndrome as a complication of treatment of oral lichen planus

O líquen plano oral (LPO) é uma doença mucocutânea inflamatória crônica relacionada com alterações na imunidade mediada por células T. Diversos medicamentos têm sido utilizados no tratamento desta doença, especialmente nas formas erosivas e ulcerativas, com resultados variados. O objetivo deste trabalho é descrever e discutir um caso clínico de líquen plano oral erosivo tratado com corticóide sistêmico que resultou em Síndrome de Cushing, que se manteve com o uso de corticóide tópico.

Oral lichen planus (OLP) is a chronic mucocutaneous inflammatory disease involving T cells-mediated immunity. Several drugs have been used to treat OLP, specially the erosive and ulcerative forms, with varying results. The aim of this paper was to describe and discuss one clinical case of erosive oral lichen planus treated with systemic corticosteroids that resulted in Cushing´s syndrome that maintained with topical corticosteroid.

Intra-oral schwannoma: case report and literature review.

Schwannoma is a relatively uncommon, slow-growing benign tumor that is derived apparently from the Schwann cells. The tongue is the most common site, followed by the palate, floor of mouth, buccal mucosa, lips, and jaws. It can present itself at any age. Usually, this lesion is not taken into account during clinical practice and the differential diagnosis includes numerous benign neoformations based on epithelial and connective tissues. Immunohistochemical features can be useful in determining the neural differentiation. Anti-S100 protein is probably the most used antibody to identify this lesion. The schwannoma is usually a solitary lesion, and can be multiple when associated with neurofibromatosis. In the current study, authors report a case of an intraoral schwannoma situated at the vestibule with 20 years of evolution treated by complete surgical excision. The diagnosis was established based on clinical, histopathological, and immunohistochemical aspects. The patient is under clinical control, with no signs of recurrence even after four years.

Estudo de anormalidades dentárias de desenvolvimento em pacientes em tratamento ortodôntico / Study of development dental abnormalities in orthodontic patients

Introdução - As estruturas do complexo maxilo-mandibular, durante o seu desenvolvimento, ficam sujeitas a sofrerem distúrbios causados por fatores ambientais, idiopáticos ou hereditários, resultando assim, em distúrbios de desenvolvimento dentário. Estas anormalidades possuem alto índice de prevalência na população em geral, e na maior parte dos trabalhos são estudadas separadamente. O presente trabalho teve o propósito de estudar a prevalência de anormalidades de desenvolvimento em pacientes em tratamento ortodôntico. Material e Método - Foram analisadas radiografias panorâmicas de 66 pacientes, sendo 39 do sexo feminino e 27 do masculino, com média de idade de 16, 16 anos, que se submeteram a tratamento ortodôntico. Resultados - Foram diagnosticadas 273 alterações e apenas 5 radiografias não apresentaram nenhuma anormalidades, as alterações mais prevalentes foram giroversão com 75,7%, retidos/impactados com 56% e agenesia com 27,2%. Conclusões - As anormalidades de desenvolvimento são alterações frequentes dos maxilares e podem ocasionar distúrbios estéticos e funcionais levando o seu portador a procurar tratamento ortodôntico

Avaliação do conhecimento sobre o câncer bucal entre universitários / Evaluation of knowledge of oral cancer among students

Introdução: O câncer oral é uma doença de alta incidência no mundo e que vem sendo considerada como problema de saúde pública. A prevenção e o diagnóstico precoce constituem as melhores formas de reverter essa situação. Objetivo: Avaliar o nível de conhecimento de uma população de universitários de Odontologia sobre o câncer de boca. Métodos: Foi aplicado um questionário contendo 37 questões para 148 alunos de Odontologia. Após a coleta, foi confeccionada uma planilha no programa de computador Excel (Microsoft). Foram comparadas as porcentagens de acerto entre os anos (teste qui-quadrado de tendência) e verificada a consistência e coerência (coeficiente de Cronbach) com nível de significância de 5% ou calculado o p-valor correspondente. As análises foram feitas utilizando-se o programa SAS for Windows, v.9.1.3. Resultados: O valor do de Cronbach para o questionário foi de 0,7681, considerado o instrumento consistente e coerente, tornando-o um método adequado para avaliação do nível de conhecimento sobre o câncer bucal. Na análise individual das questões, notou-se que, mesmo havendo diferença significativa entre algumas respostas corretas entre os anos, isso não significa que, com o passar do tempo, a porcentagem de acertos aumente. Quanto ao conhecimento sobre o câncer bucal, notou-se maior nível de acerto nos alunos de 3º e 4º ano. Os alunos demonstram alto índice de acertos quanto ao conhecimento sobre os fatores de risco do câncer bucal. Conclusão: Para melhorar o nível do conhecimento dos alunos sobre o câncer bucal, faz-se necessário um programa universitário de prevenção de câncer bucal envolvendo os alunos de todos os anos do curso.

Introduction: The oral cancer has a high incidence worldwide and it is considered a public health problem. Prevention and early diagnosis are the best solution to reverse this situation. Objective: To evaluate the level of knowledge about oral cancer in a group of Odontology students. Methods: A 37-question questionnaire was applied to 148 Odontology students. After collecting all the data, a worksheet using Microsoft Excel was created. The percentage of right answers was compared among university-level classes (Chi-square test of tendency), and the consistency and coherence were checked (Cronbach's coefficient) with 5% significance level or calculated the correspondent p-value. The analyses were conducted using the SAS system for windows 9.1.3. Results: The Cronbach's value in the questionnaire was 0.7681, considering the instrument consistent and coherent as an appropriate method to evaluate the students' level of knowledge about oral cancer. An individual analysis of the questions showed that, although there was an expressive difference in some of the right answers in different university-level classes, it does not mean that the percentage of accurate answers increases in the course of time. Regarding the level of knowledge about oral cancer, a larger number of right answers among students of the 3rd and 4th years was observed. Students had a large number of right answers concerning risk factors for oral cancer. Conclusion: It is essential to create a university program on oral cancer prevention for the students of all levels, in order to improve their knowledge about oral cancer.

Avaliação do nível de conhecimento de uma população envolvendo câncer oral / Evaluation of the level of knowledge of population involving oral cancer

Este trabalho teve como objetivo avaliar o nível de conhecimento de uma população sobre o câncer oral para o estabelecimento de estratégias eficientes de prevenção e tratamento desta doença, sendo realizadodurante duas campanhas de prevenção de câncer oral, onde setecentos e trinta e uma pessoas (731)foram examinadas, preencheram um questionário, receberam orientação sobre o auto-exame e noções básicas sobre o câncer oral. O questionário continha questões referentes à causa, sintomatologia, doençaprévia e hábitos prejudiciais relacionados ao câncer oral. Entre os participantes 43% eram homens e 57%mulheres, 24% fumantes e 21% consumidores de bebidas alcoólicas, 87% declararam ter conhecimentoda existência dessa doença, 12% já tiveram familiar com câncer oral, 57% acreditam que o câncer oralcausa dor, 44% acreditam que o fumo e 23% que o consumo de álcool está ligado à etiologia da doença. Acampanha atingiu uma população com bom conhecimento sobre o câncer e com baixo risco para o cânceroral, assim as formas de abordagem e de divulgação desses tipos de campanhas devem ser alteradas pararealmente contemplar as pessoas pertencentes ao grupo de risco para o câncer oral, que são os homenscom mais de 40 anos, fumantes, etilistas crônicos e pessoas expostas à radiação solar de maneira contínuae freqüente. Conclui-se que a verificação do nível de conhecimento sobre o câncer oral nas diferentes populaçõesé importante para que estratégias de prevenção e diagnóstico sejam estabelecidas de acordo com operfil de cada grupo.

The present work had the objective to find out the population's knowledge about oral cancer to establishefficient strategies of prevention and treatment of this disease, it was realized during two preventscampaigns of oral cancer, where seven hundred and thirty one people (731) were examined, filled a questionnaire,received orientation about the auto-exam and basic notion about oral cancer. The questionnaireincluded questions about the etiology, symptoms, previous disease and habits related to oral cancer. In thiswork 43% were men and 57% women, 24% smokers and 21% consumer of alcoholic drinks, 87% know theexisting of the disease, 12% have already had parents with oral cancer, 57% believe that the oral cancer causepain, 44% believe that tobacco and 23% that the use of alcohol is related with the etiology of the disease.The campaign achieved a population with good knowledge about cancer and with low risk to oral cancer, likethis the form of achieve and divulgation of these kinds of campaign should be modified to really achieve depeople who are the risk group, like men with more than 40 years old, smoker, alcohol's consumer and peopleexposed frequently and continuous to solar radiation. It was concluded that the level of knowledge about oralcancer in different populations is important to that strategies for the prevention and diagnosis are established according to the profile of each group.

Cisto do ducto nasopalatino: relato de caso clínico e revisão da literatura / Nasopalatine duct cyst: report of case and literature review

O cisto do ducto nasopalatino (CDNP) ou cisto do canal incisivo é considerado um cisto não-odontogênico, de patogênese incerta, que acomete indivíduos entre a 2ª e 5ª décadas de vida e exibe crescimento lento e assintomático. Radiograficamente nota-se párea radiolúcida situada na região anterior da maxila, próximo ao ápice dos incisivos centrais superiores. O diagnóstico diferencial pode ser feito com o cisto radicular, queratocisto, entretanto dados clínicos, radiográficos e histopatológicos auxiliam na conclusão do caso. Este estudo descreve um relato de caso de cisto do ducto nasopalatino observado após exame radiográfico de rotina. Foi realizada biópsia excisional para diagnóstico da lesão. O controle clínico e radiográfico pós-operatório mostrou ausência de recorrência e excelente reparo

Aspectos da doença de Hansen relevantes para o cirurgião-dentista: revisão da literatura / Relevant aspects of Hansen's disease to dentists: literature review

Tendo em vista o elevado número de casos de Doença de Hansen no Brasil, caracterizando um problema de saúde pública, o presente trabalho teve por objetivo realizar uma revisão bibliográfica visando informar o cirurgião-dentista sobre a situação atual da DH no Brasil, suas manifestações bucais, seqüelas que repercutem na saúde bucal e dar subsídios para que o profissional participe do diagnóstico desta doença